Season pork chops generously with salt, pepper, and Creole seasoning. Heat a tablespoon of oil over medium-high heat in a cast-iron or heavy Dutch oven, and sear the pork chops for about 3 minutes on each side. When ready, transfer them into the slow cooker.
Add another tablespoon of oil to the same pan, then sauté the onion, garlic, and thyme until the onions are translucent and fragrant (3-5 minutes). Next, add the mushrooms, Dijon mustard, and Italian seasoning, and sauté for another 3 minutes.
Pour in ¾ cup of water and the cream, bring to a boil, and simmer for 3-4 minutes. Adjust seasoning with salt and pepper, and pour the sauce over the pork in the slow cooker. Cook for 7-8 hours on low or 3-4 hours on high until the pork is tender and the internal temperature reaches between 145℉ (63℃) and 165℉ (74℃).
About 30 minutes before the pork chops are done, whisk the flour and ¼ cup of water in a small bowl until smooth. Pour the slurry into the slow cooker, stir gently, and continue cooking until the gravy thickens.
Serve over rice, mashed potatoes, or noodles with some veggies.